宜昌市鑫桥生产力促进中心

Yichang xin qiao productivity promotion center

研究方向

1. 药用植物及其内生菌活性次级代谢产物

2. 植物内生菌与寄主之间的相互作用

主要研究成果

1. Xue-Shuang Li, Ming-Hui Tan, Meng-Meng Lv, Cheng-Xiong Liu, Zhi-Yong Guo⁎, Liang Zhang, Kun Zou, Hai-Yan Chen⁎, Peter Proksch,New γ-pyranone and nucleoside derivatives from Penicillium sp., Phytochemistry Letters 2017,20 : 285–288.

2. Zi-Wei Feng, Meng-Meng Lv, Xue-Shuang Li, Liang Zhang, Cheng-Xiong Liu, Zhi-Yong Guo*, Zhang-Shuang Deng*, Kun Zou, Peter Proksch, Penicitroamide, an Antimicrobial Metabolite with High Carbonylization from the Endophytic Fungus Penicillium sp. (NO. 24), Molecules 2016, 21(11), 1438-1446.

3. Zhiyong Guo, Xueshuang Li, Liang Zhang, Ziwei Feng, Zhangshuang Deng, Haibo He & Kun Zou,Cytotoxic tremulanes and 5,6-secotremulanes, four new sesquiterpenoids from a plantassociated fungus X1-2,Natural Product Research, 2016(30) 22: 2582–258.

4. Qiao Wan, Ziwei Feng, Xueshuang Li, Mengmeng Lv, Zhiyong Guo*, Zhangshuang Deng*, Kun Zou, Two new glycosidal metabolites of endophytic fungus Penicillium sp. (NO.4) from Tapiscia sinensis, Z. Naturforsch. 2016,71b (4): 283–286.

5. Cheng-XiongLiu,*Xiao-QinYu,Zhi-YongGuo,Hai-Bo He,XuanTu, Zhang-Shuang Deng and Kun Zou,Structural elucidation and NMR spectral assignments of paraconfuranones I–M from the insect-associated fungus Paraconiothyrium brasiliense, Magn. Reson. Chem. 2016, 54(11):916–921.

6. Cai-Juan Zheng, Chang-Lun Shao, Zhi-Yong Guo, Jian-Feng Chen, Dong-Sheng Deng, Kai-Lin Yang, Yi-Yan Chen, Xiu-Mei Fu,Zhi-Gang She, Yong-Cheng Lin, and Chang-Yun Wang,Bioactive Hydroanthraquinones and Anthraquinone Dimers from a Soft Coral-Derived Alternaria sp. Fungus,J. Nat. Prod. 2012, 75, 189−197.

7. Cheng-Xiong Liu, Zhi-Yong Guo, Yan-Hong Xue, Jun Cheng, Nian-Yu Huang, Yuan Zhou, Fan Cheng, Kun Zou,Five new furostanol saponins from the rhizomes of Tupistra chinensis,Fitoterapia,2012,83:323–328.

8. Ling-Ling Sun, Chang-Lun Shao, Jian-Feng Chen, Zhi-Yong Guo, Xiu-Mei Fu, Min Chen, Yi-Yan Chen, Rui Li, Nicole J. de Voogd, Zhi-Gang She, Yong-Cheng Lin, Chang-Yun Wang, New bisabolane sesquiterpenoids from a marine-derived fungus Aspergillus sp. isolated from the sponge Xestospongia testudinaria, Bioorganic & Medicinal Chemistry Letters,2012,22(2):1323-1326

奖励:

1.《三峡区域典型土家族要用植物开发应用研究》获民族医药科学技术协会科技进步二等奖(排名第四)

2.《湖北海棠活性物质基础及开发利用研究》项目获湖北省科技进步二等奖(排名第四),

 

近五年科研项目

1.国家自然科学基金面上项目——《七叶一枝花(真菌和放线菌)单培养和共培养选择性抑制肝癌细胞活性次级代谢产物研究(21272137)》,2013.1-2016.12

2.国家自然科学基金青年项目《银鹊树内生真菌抗肺癌活性次级代谢产物研究(21002058)》,2011.1-2013.12